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发布于:2018-6-13 12:46:53  访问:39 次 回复:0 篇
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Model for depression and of the factors influencing its implementation in
We are going to recruit 540 sufferers with 180 randomised to each arm. Individuals is going to be reassessed at six, 12, 36, 52 and 86 weeks. Methodological aspects on the study are systematic recruitment, explicit inclusion criteria, reliability checks of assessments with manage for rater shift, investigation assessors independent of remedy team and blind to randomization, evaluation by intention to treat, data management employing remote data entry, measures of high quality assurance, sophisticated statistical evaluation, manualised 51-77-4 treatment protocols, checks of adherence and competence of therapists and assessment of cost-effectiveness. We are going to also identify whether or not time to recovery srep43317 and/or relapse are moderated by variations in brain structure and function and chosen genetic and hormone biomarkers taken at entry.* CS-6352 Correspondence: ig104@cam.ac.uk 1 Department of Psychiatry, University of Cambridge as well as the Cambridge and Peterborough Foundation Trust, Douglas Residence, 18b Trumpington Road Cambridge, UK Full list of author info is availa.Model for depression and of the factors influencing its implementation inside the key care setting in the Netherlands. Int J Integr Care 2009, 9:e81.doi:10.1186/1745-6215-12-121 Cite this short article as: Chen et al.: Depression care management for latelife depression in China key care: Protocol for a randomized controlled trial. Trials 2011 12:121.Submit your next manuscript to BioMed Central and take full benefit of:?Handy on line submission ?Thorough peer assessment ?No space constraints or color figure charges ?Immediate publication on acceptance ?Inclusion in PubMed, CAS, Scopus and Google Scholar ?Investigation which is freely available for redistributionSubmit your manuscript at www.biomedcentral.com/submit
Goodyer et al. Trials 2011, 12:175 http://www.trialsjournal.com/content/12/1/TRIALSOpen AccessSTUDY PROTOCOLImproving mood with psychoanalytic and cognitive therapies (Effect): a pragmatic effectiveness superiority trial to investigate whether or not specialised psychological therapy reduces the risk for relapse in adolescents with moderate to severe unipolar depression: study protocol for any randomised controlled trialIan M Goodyer1*, Sonya Tsancheva1, Sarah Byford2, jir.2014.0149 Bernadka Dubicka3, Jonathan Hill3, Raphael Kelvin1, Shirley Reynolds four, Christopher Roberts5, Robert Senior6, John Suckling7, Paul Wilkinson1, Mary Target8 and Peter FonagyAbstractBackground: Up to 70 of adolescents with moderate to serious unipolar big depression respond to psychological treatment plus Fluoxetine (20-50 mg) with symptom reduction and enhanced social function reported by 24 weeks following starting treatment. Around 20 of non responders appear treatment resistant and 30 of responders relapse inside 2 years. The particular efficacy of unique psychological therapies and also the moderators and mediators that influence danger for relapse are unclear. The cost-effectiveness and security of psychological treatment options stay poorly evaluated. Methods/Design: Improving Mood with Psychoanalytic and Cognitive Therapies, the Influence Study, will identify irrespective of whether Cognitive Behavioural Therapy or Short Term Psychoanalytic Therapy is superior in lowering relapse compared with Specialist Clinical Care. The study is really a multicentre pragmatic effectiveness superiority randomised clinical trial: Cognitive Behavioural Therapy consists of 20 sessions more than 30 weeks, Short Term Psychoanalytic Psychotherapy 30 sessions more than 30 weeks and Specialist Clinical Care 12 sessions more than 20 weeks. We will recruit 540 individuals with 180 randomised to each arm. Sufferers might be reassessed at six, 12, 36, 52 and 86 weeks.
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